Re-enable your mods with the Nexus Mod Manager.Run Fallout 4 but don't push 'Play' on the game's launcher.In the meantime, players have discovered the following workaround: I'd imagine many modders are doing just that right now. Game patches often disrupt mods' functioning, forcing the creators of those mods to update them. This doesn't seem to be a conscious effort on Bethesda's part. Players are reporting that mods are being disabled by Fallout 4's launcher.